HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 18412321, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Ammonium Carbonate | HCID 517111 | — |
| Reactant | 2-[N-(4-cyanophenyl)aminomethyl]benzothiazol-5-yl-carboxylic acid-N-(n-propyl)-N-(2-ethoxycarbonylethyl)amide | HCID 18412429 | — |
| Catalyst | Acetic Acid | HCID 176 | — |
| Solvent | Dichloromethane ethanol | HCID 21584144 | — |
| Product | HCID 18412321 | HCID 18412321 | 83% |
Reaction Steps
Prepared analogously to Example 9 from 2-[N-(4-cyanophenyl)aminomethyl]benzothiazol-5-yl-carboxylic acid-N-(n-propyl)-N-(2-ethoxycarbonylethyl)amide, ethanolic hydrochloric acid, ethanol, and ammonium carbonate. Yield: 83% of theory, C24H29N5O3 (467.59); Rf value: 0.31 (silica gel; methylene chloride/ethanol=4:1+a few drops of acetic acid); EKA mass spectrum: (M+H)+=468; (2M+H)+=935.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06710055B2 |
| Source dataset | uspto-grants-2004_03 |
| ORD ID | ord-a30ee33bd49149a4b98c2fc5a19c4a92 |
| Source note | uspto-grants-2004_03 |