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HRID50226

反应详情

EQUATION

反应方程式

HRID 50226 的结构方程式

REACTANTS

反应物

2
结构：[Na+].[OH-]
HCID14798

Sodium Hydroxide

HNaO

结构：CCCN(CCC(=O)OCC)C(=O)c1ccc2sc(CNc3ccc(C(=N)N)cc3)nc2c1.Cl
HCID18412321

未命名化合物

PRODUCTS

生成物

1
结构：CCCN(CCC(=O)O)C(=O)c1ccc2sc(CNc3ccc(C(=N)N)cc3)nc2c1.Cl
HCID18412374

未命名化合物

收率 75%

AUXILIARIES

试剂、催化剂与溶剂

2
结构：CC(=O)O
催化剂HCID176

Acetic Acid

C2H4O2

结构：CCO.ClCCl
溶剂HCID21584144

Dichloromethane ethanol

C3H8Cl2O

PROCEDURE

实验过程

Prepared analogously to Example 10 from 2-[N-(4-amidinophenyl)aminomethyl]benzothiazol-5-yl-carboxylic acid-N-(n-propyl)-N-(2-ethoxycarbonylethyl)amide hydrochloride and sodium hydroxide solution. Yield: 75% of theory, C22H25N5O3S (439.54); Rf value: 0.14 (silica gel; methylene chloride/ethanol=4:1+a few drops of acetic acid); EKA mass spectrum: (M+H)+=440; (M+H+Na)++=231.6.