HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-[(Tert-butoxy)carbonyl]piperidine-2-carboxylic acid → HCID 22977785, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-[(Tert-butoxy)carbonyl]piperidine-2-carboxylic acid | HCID 581831 | — |
| Reactant | (2-Benzyloxy-5-oxo-tetrahydro-furan-3-yl)-carbamic acid allyl ester | HCID 22321532 | — |
| Product | HCID 22977785 | HCID 22977785 | 85.9% |
Reaction Steps
Reaction of N-tert-butoxycarbonylpipecolic acid (460 mg, 2.0 mmol) and N-allyloxycarbonyl-4-amino-5-benzyloxy-2-oxotetrahydrofuran (530 mg, 1.82 mmol) was carried out by a method analogous to that reported by Chapman (Bioorg. & Med. Chem. Lett. 1992, 2, 613-618.) to give 654 mg of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07772366B2 |
| Source dataset | uspto-grants-2010_08 |
| ORD ID | ord-3f6d2a5966e04dcf8836eef5d969cb25 |
| Source note | uspto-grants-2010_08 |