HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(Morpholin-4-yl)isonicotinic acid → N-[1-(4-Chloro-3-ethoxy-benzyl)piperidin-4-yl]-2-morpholin-4-yl-isonicotinamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(Morpholin-4-yl)isonicotinic acid | HCID 2762479 | — |
| Reactant | 1-(4-Chloro-3-ethoxybenzyl)piperidin-4-ylamine | HCID 59210377 | — |
| Product | N-[1-(4-Chloro-3-ethoxy-benzyl)piperidin-4-yl]-2-morpholin-4-yl-isonicotinamide | HCID 68458047 | 34% |
Reaction Steps
The title compound (16 mg, 34%) was prepared analogously to example 1 by coupling of 1-(4-chloro-3-ethoxy-benzyl)piperidin-4-ylamine with 2-(4-morpholinyl)-4-pyridinecarboxylic acid. MS: 459.4 (MH+)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07772253B2 |
| Source dataset | uspto-grants-2010_08 |
| ORD ID | ord-395af3589c2942598d92f9ca82a6735c |
| Source note | uspto-grants-2010_08 |