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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 502346Generated: October 26, 2026

2,5-Dimethylbenzoic acid → N-[1-(4-Chloro-3-ethoxy-benzyl)piperidin-4-yl]-2,5-dimethyl-benzamide

https://huagongshe.com/reaction/502346

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,5-Dimethylbenzoic acidHCID 11892—
Reactant1-(4-Chloro-3-ethoxybenzyl)piperidin-4-ylamineHCID 59210377—
ProductN-[1-(4-Chloro-3-ethoxy-benzyl)piperidin-4-yl]-2,5-dimethyl-benzamideHCID 6845930910%

Reaction Steps

The title compound (4 mg, 10%) was prepared analogously to example 8 by coupling of 1-(4-chloro-3-ethoxy-benzyl)piperidin-4-ylamine with 2,5-dimethylbenzoic acid. MS: 401.4 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07772253B2
Source datasetuspto-grants-2010_08
ORD IDord-22c95d12cd44435d9ffd2eb638b023ee
Source noteuspto-grants-2010_08