Ethyl 2,6-diethoxy-4-formylbenzoate → HCID 68456685, compound

HRID 502363Notes

Reaction equation

HRID 502363 reaction equation
[CH3:1][C:2]1[CH:3]=[N:4][CH:5]=[C:6]([CH:16]=1)[C:7]([NH:9][CH:10]1[CH2:15][CH2:14][NH:13][CH2:12][CH2:11]1)=[O:8].[CH2:17]([O:19][C:20]1[CH:21]=[C:22]([CH:25]=[C:26]([O:33][CH2:34][CH3:35])[C:27]=1[C:28]([O:30][CH2:31][CH3:32])=[O:29])[CH:23]=O)[CH3:18]>>[CH2:34]([O:33][C:26]1[CH:25]=[C:22]([CH:21]=[C:20]([O:19][CH2:17][CH3:18])[C:27]=1[C:28]([O:30][CH2:31][CH3:32])=[O:29])[CH2:23][N:13]1[CH2:12][CH2:11][CH:10]([NH:9][C:7](=[O:8])[C:6]2[CH:16]=[C:2]([CH3:1])[CH:3]=[N:4][CH:5]=2)[CH2:15][CH2:14]1)[CH3:35]

Participants

3

Reactant 2

HCID 20288848Ethyl 2,6-diethoxy-4-formylbenzoateHCID 655621085-Methyl-N-(piperidin-4-yl)-nicotinamide

Product 1

HCID 68456685HCID 68456685, compoundYield 32%

Procedure

The title (15 mg, 32%) compound was prepared analogously to example 30 from 5-methyl-N-(piperidin-4-yl)-nicotinamide and 3,5-diethoxy-4-ethoxycarbonyl-benzaldehyde. MS: 470.5 (MH+)

Sources & evidence

ORD record
ord-65b186c59f714b688ace0e0aa745a784
Source dataset
uspto-grants-2010_08
Patent number
US07772253B2

Reaction notes

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