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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 502364Generated: October 26, 2026

3-Ethoxy-4-fluorobenzaldehyde → N-[1-(3-Ethoxy-4-fluoro-benzyl)piperidin-4-yl]-5-methyl-nicotinamide

https://huagongshe.com/reaction/502364

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Ethoxy-4-fluorobenzaldehydeHCID 42614294—
Reactant5-Methyl-N-(piperidin-4-yl)-nicotinamideHCID 65562108—
ProductN-[1-(3-Ethoxy-4-fluoro-benzyl)piperidin-4-yl]-5-methyl-nicotinamideHCID 6845720030%

Reaction Steps

The title compound (11 mg, 30%) was prepared analogously to example 30 from 5-methyl-N-(piperidin-4-yl)-nicotinamide and 3-ethoxy-4-fluoro-benzaldehyde. MS: 372.5 (MH+)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07772253B2
Source datasetuspto-grants-2010_08
ORD IDord-8ee9093384594696a4dd11d02ce8b963
Source noteuspto-grants-2010_08