HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetyl chloride → 5-Acetylamino-N-[1-(4-chloro-3-ethoxy-benzyl)piperidin-4-yl]-nicotinamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetyl chloride | HCID 6367 | — |
| Reactant | 5-Amino-N-[1-(4-chloro-3-ethoxy-benzyl)piperidin-4-yl]-nicotinamide | HCID 68457178 | — |
| Product | 5-Acetylamino-N-[1-(4-chloro-3-ethoxy-benzyl)piperidin-4-yl]-nicotinamide | HCID 68459109 | 26% |
Reaction Steps
The title compound (12 mg, 26%) was prepared analogously to example 7 by coupling of 5-amino-N-[1-(4-chloro-3-ethoxy-benzyl)piperidin-4-yl]-nicotinamide with acetyl chloride. MS: 431.4 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07772253B2 |
| Source dataset | uspto-grants-2010_08 |
| ORD ID | ord-b69736d535f345fc81120b0d8e3301c1 |
| Source note | uspto-grants-2010_08 |