HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(Methoxycarbonyl)benzoic acid → N-[1-(4-Chloro-3-ethoxy-benzyl)-piperidin-4-yl]-isophthalamic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(Methoxycarbonyl)benzoic acid | HCID 601880 | — |
| Reactant | 1-(4-Chloro-3-ethoxybenzyl)piperidin-4-ylamine | HCID 59210377 | — |
| Product | N-[1-(4-Chloro-3-ethoxy-benzyl)-piperidin-4-yl]-isophthalamic acid methyl ester | HCID 68458702 | 92% |
Reaction Steps
The title compound (80 mg, 92%) was prepared analogously to example 8 by coupling of 1-(4-chloro-3-ethoxy-benzyl)piperidin-4-ylamine with isophthalic acid monomethyl ester. MS: 431.6 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07772253B2 |
| Source dataset | uspto-grants-2010_08 |
| ORD ID | ord-410297f82ade45b1a62dcb3dc7c537ee |
| Source note | uspto-grants-2010_08 |