HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Diisopropylethylamine → HCID 178466701, Verbindung
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Diisopropylethylamine | HCID 81531 | — |
| Edukt | Sodium cyanoborohydride | HCID 5003444 | — |
| Edukt | 3,5-diethoxy-4-(1H-pyrrol-1-yl)benzaldehyde | HCID 53486013 | — |
| Edukt | HCID 178493414 | HCID 178493414 | — |
| Lösungsmittel | Acetic Acid | HCID 176 | — |
| Lösungsmittel | Ethanol | HCID 702 | — |
| Produkt | HCID 178466701 | HCID 178466701 | — |
Reaktionsschritte
In analogy to the procedure described in example 50k), 3-methoxy-N-piperidin-4-yl-5-(1H-tetrazol-5-ylmethoxy)-benzamide (example 170c) was reacted with 3,5-diethoxy-4-pyrrol-1-yl-benzaldehyde (example 40b), sodium cyanoborohydride, N-ethyl-diisopropylamine and acetic acid in ethanol at 50° C. to yield the title compound as off-white solid. MS: 576.2 (MH+).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07772253B2 |
| Quelldatensatz | uspto-grants-2010_08 |
| ORD ID | ord-77440c717cfc4f299834a26d94381af7 |
| Quellennotiz | uspto-grants-2010_08 |