反应详情

2-Isopropyl-1-methoxy-4-nitro-benzene (4.53 g, 23.6 mmol) was dissolved in 100 mL of methanol in presence of 0.4 g of 10% Pd/C in a Parr bottle, and then subjected to 40 psi of H2 overnight at room temperature. The mixture was purged with nitrogen for 10 minutes and filtered over Celite. The filtrate was concentrated to give 4.22 g 3-isopropyl-4-methoxyaniline.

1. customsubjected to 40 psi of H2 overnight at room temperature
2. customThe mixture was purged with nitrogen for 10 minutes
3. filtrationfiltered over Celite
4. concentrationThe filtrate was concentrated