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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 50265Generated: October 26, 2026

Sodium Hydroxide → HCID 18412334, compound

https://huagongshe.com/reaction/50265

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
Reactant1-methyl-2-[2-(4-amidinophenyl)ethyl]benzimidazol-5-yl-carboxylic acid-N-(2-pyridyl)-N-(2-ethoxycarbonylethyl)amide hydrochlorideHCID 18412669—
ProductHCID 18412334HCID 1841233497%

Reaction Steps

Prepared analogously to Example 26 from 1-methyl-2-[2-(4-amidinophenyl)ethyl]benzimidazol-5-yl-carboxylic acid-N-(2-pyridyl)-N-(2-ethoxycarbonylethyl)amide hydrochloride and sodium hydroxide solution. Yield: 97% of theory, C26H26N6O3 (470.5); EKA mass spectrum: (M+H)+=471; (M+H+Na)++=247; (M+Na)+=493.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06710055B2
Source datasetuspto-grants-2004_03
ORD IDord-595a1adee7ab4bb1a15a957279b61e80
Source noteuspto-grants-2004_03