1,3-Propanediamine, N1,N1,N3-trimethyl- → N-(3-(dimethylamino)propyl)-N-methyl-2-nitro-4-(trifluoromethyl)benzenesulfonamide

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To a solution of 2-nitro-4-(trifluoromethyl)benzene-1-sulfonyl chloride (500 mg, 1.73 mmol) in CH2Cl2 (5 ml) was added N1,N1,N3-trimethylpropane-1,3-diamine (0.26 ml, 1.8 mmol). The resulting mixture was allowed to stir at room temperature for 20 min. Diluted with CH2Cl2 (30 ml) and washed the organic layer with 9% aq. Na2CO3 (10 ml) and brine (10 ml). Dried over anhydrous sodium sulfate, filtered and concentrated to a white solid, which was used without further purification. MS m/z=370.1 [M+H]+. Calc'd for C13H18F3N3O4S: 369.4.

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