N,N-dimethyl-3-(4-nitrophenoxy)propan-1-amine → 4-(3-(Dimethylamino)propoxy)aniline

Participants

Reaction Steps

4-(3-(dimethylamino)propoxy)nitrobenzene (4.4 g, 19.6 mmol) was hydrogenated over Pd (10% on C, 0.4 g) in ethanol (50 ml) for 16 h. The catalyst was filtered off and the solvent removed under reduced pressure to afford the title compound as a brown oil. MS (m/z)=195.3 (M+H+); Calc'd for C11H18N2O=194.28.

Provenance & Evidence