HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → 1-Methyl-2-[N-(4-amidinophenyl)-N-methlaminomethyl]benzimidazol-5-yl-carboxylic acid-N-(2-pyridyl)-N-(2-hydroxycarbonylethyl)amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 1-methyl-2-[N-(4-amidinophenyl)-N-methylaminomethyl]benzimidazol-5-yl-carboxylic acid-N-(2-pyridyl)-N-(2-ethoxycarbonylethyl)amide hydrochloride | HCID 18412298 | — |
| Product | 1-Methyl-2-[N-(4-amidinophenyl)-N-methlaminomethyl]benzimidazol-5-yl-carboxylic acid-N-(2-pyridyl)-N-(2-hydroxycarbonylethyl)amide | HCID 18412393 | 66% |
Reaction Steps
Prepared analogously to Example 26 from 1-methyl-2-[N-(4-amidinophenyl)-N-methylaminomethyl]benzimidazol-5-yl-carboxylic acid-N-(2-pyridyl)-N-(2-ethoxycarbonylethyl)amide hydrochloride and sodium hydroxide solution. Yield: 66% of theory, C26H27N7O3 (485.6); EKA mass spectrum: (M+H)+=486; (M+Na)+=508; (M+2Na)++=265.6.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06710055B2 |
| Source dataset | uspto-grants-2004_03 |
| ORD ID | ord-1425f2c350c54162b53d9711ae9bd24b |
| Source note | uspto-grants-2004_03 |