3-Bromo-4-fluorobenzoyl chloride → 4-Chloro-3-iodobenzoyl chloride

HRID 502778Notes

Reaction equation

HRID 502778 reaction equation
[Cl:1][C:2]1[CH:10]=[CH:9][C:5]([C:6](O)=[O:7])=[CH:4][C:3]=1[I:11].BrC1C=C(C=CC=1F)C([Cl:18])=O>>[Cl:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([Cl:18])=[O:7])=[CH:4][C:3]=1[I:11]

Participants

3

Reactant 2

HCID 695983-Bromo-4-fluorobenzoyl chlorideHCID 27576164-Chloro-3-iodobenzoic acid

Product 1

HCID 573499404-Chloro-3-iodobenzoyl chloride

Procedure

4-Chloro-3-iodobenzoylchloride was prepared from 4-chloro-3-iodobenzoic acid according to the procedure described in Example 183 for the synthesis of 3-bromo-4-fluorobenzoyl chloride.

Sources & evidence

ORD record
ord-66892135769f47daa8a2d549322a8939
Source dataset
uspto-grants-2010_08
Patent number
US07776869B2

Reaction notes

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