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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 50278Generated: November 2, 2026

Sodium Hydroxide → HCID 18412505, compound

https://huagongshe.com/reaction/50278

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
Reactant1-methyl-2-[2-(4-amidinophenyl)ethyl]benzimidazol-5-yl-carboxylic acid-N-cyclopentyl-N-(2-ethoxycarbonylethyl)amide hydrochlorideHCID 18412709—
ProductHCID 18412505HCID 1841250589%

Reaction Steps

Prepared analogously to Example 26 from 1-methyl-2-[2-(4-amidinophenyl)ethyl]benzimidazol-5-yl-carboxylic acid-N-cyclopentyl-N-(2-ethoxycarbonylethyl)amide hydrochloride and sodium hydroxide solution. Yield: 89% of theory, C26H31N5O3 (461.6); EKA mass spectrum: (M+H)+=462; (M+H+Na)++=242.6; (M+Na)+=484; (M+2H)++=231.6.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06710055B2
Source datasetuspto-grants-2004_03
ORD IDord-41f2224cb0734fa5a0388d5eb1320a46
Source noteuspto-grants-2004_03