HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,6-Dioxaspiro[2.5]octane → HCID 59255059, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,6-Dioxaspiro[2.5]octane | HCID 160439 | — |
| Reactant | Tert-butyl (piperidin-4-ylmethyl)carbamate | HCID 723429 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 59255059 | HCID 59255059 | — |
Reaction Steps
To a stirred solution of tert-butyl(piperidin-4-ylmethyl)carbamate (22.3 g, 104 mmol) in methanol was added 1,6-dioxaspiro[2.5]octane (14.2 g, 124 mmol, Satyamurthy, Nagichettiar et al., Phosphorus Sulfur, 1984, 19, 113) at ambient temperature.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07776885B2 |
| Source dataset | uspto-grants-2010_08 |
| ORD ID | ord-4915662e86cd4417b09f827755efa109 |
| Source note | uspto-grants-2010_08 |