Potassium Hydroxide → HCID 68467931, compound
Reaction equation
[CH2:1]([N:8]1[CH2:13][CH2:12][CH:11]([C:14]2([C:19]([O:21]CC)=[O:20])[CH2:18][CH2:17][CH2:16][CH2:15]2)[CH2:10][CH2:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[OH-].[K+]>C(O)CO>[CH2:1]([N:8]1[CH2:9][CH2:10][CH:11]([C:14]2([C:19]([OH:21])=[O:20])[CH2:15][CH2:16][CH2:17][CH2:18]2)[CH2:12][CH2:13]1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
Ethyl 1-(1-benzylpiperidin-4-yl)cyclopentanecarboxylate was reacted with potassium hydroxide in ethylene glycol under heating to obtain 1-(1-benzylpiperidin-4-yl)cyclopentanecarboxylic acid.
Workup
- temperatureunder heating
Sources & evidence
- ORD record
- ord-eb6a28a0871144c1ba7e52415e30102e
- Source dataset
- uspto-grants-2010_08
- Patent number
- US07776897B2
Reaction notes
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