Hexyl chloroformate → methyl 3-(2-(((4-(N-((hexyloxy)carbonyl)carbamimidoyl)phenyl)amino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoate

Beteiligte Stoffe

Reaktionsschritte

Prepared analogously to Example 90 from 1-methyl-2-[N-(4-amidinophenyl)aminomethyl]benzimidazol-5-yl-carboxylic acid-N-(2-pyridyl)-N-(2-methoxycarbonylethyl)amide hydrochloride and n-hexyl chloroformate. Yield: 51% of theory, C33H39N7O5 (613.7); Rf value: 0.56 (silica gel; dichloromethane/methanol=9:1); EKA mass spectrum: (M+H)+=614; (M+H+Na)++=318.7; (M+2H)++=307.6.

Herkunft & Nachweise