HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl chloroformate → HCID 140409612, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl chloroformate | HCID 6586 | — |
| Reactant | 1-methyl-2-[N-(4-amidinophenyl)aminomethyl]benzimidazol-5-yl-carboxylic acid-N-(2-pyridyl)-N-ethoxycarbonylmethylamide hydrochloride | HCID 18412300 | — |
| Solvent | Dichloromethane ethanol | HCID 21584144 | — |
| Product | HCID 140409612 | HCID 140409612 | 62% |
Reaction Steps
Prepared analogously to Example 90 from 1-methyl-2-[N-(4-amidinophenyl)aminomethyl]benzimidazol-5-yl-carboxylic acid-N-(2-pyridyl)-N-ethoxycarbonylmethylamide hydrochloride and methyl chloroformate. Yield: 62% of theory, C28H29N7O5 (543.6); Rf value: 0.19 (silica gel; dichloromethane/ethanol=19:1); EKA mass spectrum: (M+H)+=544; (M+H+Na)++=283.8; (M+Na)+=566.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06710055B2 |
| Source dataset | uspto-grants-2004_03 |
| ORD ID | ord-24af0a402d4e48d6bbaf03b720085c87 |
| Source note | uspto-grants-2004_03 |