Sodium Hydroxide → HCID 18412732, compound

Participants

Reaction Steps

Prepared analogously to Example 10 from 1-methyl-2-[(4-amidinophenyl)methylthio]benzimidazol-5-yl-carboxylic acid-N-phenyl-N-(2-ethoxycarbonylethyl)amide hydrochloride and sodium hydroxide solution. Yield: 57% of theory, C26H25N5O3S (487.58); Rf value: 0.23 (Reversed Phase silica gel RP-8; Methanol/5% saline solution=6:4); EKA mass spectrum: (M+H)+=488; (M+Na)+=510; (M+Na+H)++=255.6.

Provenance & Evidence