HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 18412309, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Ammonium Carbonate | HCID 517111 | — |
| Reactant | 1-Methyl-2[n-(4-cyanophenyl)aminomethyl]benzimidazol-5-yl-sulfonic acid-n-phenyl-n-(2-ethoxycarbonylethyl)amide | HCID 18412329 | — |
| Solvent | Dichloromethane ethanol | HCID 21584144 | — |
| Product | HCID 18412309 | HCID 18412309 | 87% |
Reaction Steps
Prepared analogously to Example 25d from 1-methyl-2-[N-(4-cyanophenyl)aminomethyl]benzimidazol-5-yl-sulfonic acid-N-phenyl-N-(2-ethoxycarbonylethyl)amide, ethanolic hydrochloric acid, ethanol, and ammonium carbonate. Yield: 87% of theory, C27H30N6O4S (534.6); Rf value: 0.13 (silica gel; dichloromethane/ethanol=9:1); EKA mass spectrum: (M+H)+=535; (M+H+Na)++=279.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06710055B2 |
| Source dataset | uspto-grants-2004_03 |
| ORD ID | ord-b3c1382c5ea443488df98bb39f6a5f60 |
| Source note | uspto-grants-2004_03 |