HRID50361

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID14798

Sodium Hydroxide

HNaO

结构：CCOC(=O)CCN(c1ccccc1)S(=O)(=O)c1ccc2c(c1)nc(CNc1ccc(C(=N)N)cc1)n2C.Cl

HCID18412309

未命名化合物

PRODUCTS

生成物

结构：Cn1c(CNc2ccc(C(=N)N)cc2)nc2cc(S(=O)(=O)N(CCC(=O)O)c3ccccc3)ccc21

HCID18412456

未命名化合物

收率 24%

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID887

Methanol

CH4O

PROCEDURE

实验过程

Prepared analogously to Example 26 from 1-methyl-2-[N-(4-amidinophenyl)aminomethyl]benzimidazol-5-yl-sulfonic acid-N-phenyl-N-(2-ethoxycarbonylethyl)amide hydrochloride and sodium hydroxide solution. Yield: 24% of theory, C25H26N6O4S (506.6); Rf value: 0.55 (Reverse-Phase RP-18 silica gel; methanol/5% saline solution=3:2); EKA mass spectrum: (M+H)+=507; (M+Na)+=529; (M+2Na)++=276.