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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 503699Generated: October 26, 2026

Methanaminium, N-((dimethylamino)(3H-1,2,3-triazolo(4,5-b)pyridin-3-yloxy)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1) → 2-Iodo-5-[(2-(3-fluorophenyl)butanoyl)amino]benzamide

https://huagongshe.com/reaction/503699

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethanaminium, N-((dimethylamino)(3H-1,2,3-triazolo(4,5-b)pyridin-3-yloxy)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)HCID 9886157—
Reactant5-Amino-2-iodobenzamideHCID 15547622—
Reactant2-(3-Fluorophenyl)butanoic acidHCID 22275741—
Product2-Iodo-5-[(2-(3-fluorophenyl)butanoyl)amino]benzamideHCID 68688547—

Reaction Steps

2-Iodo-5-[(2-(3-fluorophenyl)butanoyl)amino]benzamide is prepared from 5-amino-2-iodobenzamide and 2-(3-fluorophenyl)butanoic acid under standard amide coupling conditions with HATU.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07776922B2
Source datasetuspto-grants-2010_08
ORD IDord-2cec9beeb39a49f08c4cc812c38f64ac
Source noteuspto-grants-2010_08