反应详情

100 mg 4-(6-phenyl-3-vinylimidazo[1,2-a]pyrimidin-7-yl)benzaldehyde (prepared as described under example 15 are dissolved in a mixture of 5 ml THF and 5 ml EtOH. 10 mg 10% Pd/C are added and the mixture stirred under an atmosphere of hydrogen for 2 h. The mixture is filtered of celite, the solvens is evaporated and the crude product is purified by chromatography on silica gel (dichloromethane/methanol).

1. filtrationThe mixture is filtered of celite
2. customthe solvens is evaporated
3. customthe crude product is purified by chromatography on silica gel (dichloromethane/methanol)