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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 5038Generated: October 25, 2026

Indole → Methyl (E)-11-[2-(7-aza-1-indolyl)ethylidene]-6,11-dihydrodibenz[b,e]oxepin-2-carboxylate

https://huagongshe.com/reaction/5038

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIndoleHCID 798—
ReactantBenzimidazoleHCID 5798—
ReactantMethyl (E)-11-(2-chloroethylidene)-6,11-dihydrodibenz[b,e]oxepin-2-carboxylateHCID 10448388—
ProductMethyl (E)-11-[2-(7-aza-1-indolyl)ethylidene]-6,11-dihydrodibenz[b,e]oxepin-2-carboxylateHCID 15704217—

Reaction Steps

In Examples 40 through 49, the products were prepared in a manner similar to Example 23, using Compound h and the corresponding benzimidazole or indole derivatives.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05242931
Source datasetuspto-grants-1993_09
ORD IDord-c5ae183eb4bd4d98998488c4391b784a
Source noteuspto-grants-1993_09