HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 18412435, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Ammonium Carbonate | HCID 517111 | — |
| Reactant | HCID 18412724 | HCID 18412724 | — |
| Solvent | Dichloromethane methanol | HCID 21226129 | — |
| Product | HCID 18412435 | HCID 18412435 | 42% |
Reaction Steps
Prepared analogously to Example 25d from 1-methyl-2-[N-(4-cyanophenyl)aminomethyl]benzimidazol-5-yl-carboxylic acid-N-(3-fluorophenyl)-N-(2-ethoxycarbonylethyl)amide and ethanolic hydrochloric acid, ethanol, and ammonium carbonate. Yield: 42% of theory, C28H29FN6O3 (516.6); Rf value: 0.31 (silica gel; dichloromethane/methanol 5:1); EKA mass spectrum: (M+H)+=517; (M+H+Na)++=270.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06710055B2 |
| Source dataset | uspto-grants-2004_03 |
| ORD ID | ord-e9a566db00664d79b7b0cfb13de1dc0d |
| Source note | uspto-grants-2004_03 |