HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydroxylamine → HCID 178480671, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydroxylamine | HCID 787 | — |
| Reactant | 1-methyl-2-[N-(4-cyanophenyl)aminomethyl]benzimidazol-5-yl-carboxylic acid-N-(2-pyridyl)-N-[2-(methanesulfonylaminocarbonyl)ethyl]amide | HCID 18412590 | — |
| Reactant | Dichloromethane ethanol | HCID 21584144 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | HCID 178480671 | HCID 178480671 | 27% |
Reaction Steps
Prepared analogously to Example 96 from 1-methyl-2-[N-(4-cyanophenyl)aminomethyl]benzimidazol-5-yl-carboxylic acid-N-(2-pyridyl)-N-[2-(methanesulfonylaminocarbonyl)ethyl]amide and hydroxylamine. Yield: 27% of theory, C26H28N8O5S (564.6); Rf value: 0.75 (silica gel; dichloromethane/ethanol=7:3+1% glacial acetic acid); EKA mass spectrum: (M+H)+=565; (M+Na)+=587.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06710055B2 |
| Source dataset | uspto-grants-2004_03 |
| ORD ID | ord-56e577b7d629447996fbe8d7dc4ffb32 |
| Source note | uspto-grants-2004_03 |