Sodium Hydroxide → HCID 135690256, compound

HRID 50402Notes

Reaction equation

Cl.[N:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[N:8]([CH2:31][CH2:32][C:33]([O:35]CC)=[O:34])[C:9]([C:11]1[CH:30]=[CH:29][C:14]2[N:15]([CH3:28])[C:16]([CH2:18][NH:19][C:20]3[S:21][C:22]([C:25](=[NH:27])[NH2:26])=[CH:23][N:24]=3)=[N:17][C:13]=2[CH:12]=1)=[O:10].[OH-].[Na+]>>[N:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[N:8]([CH2:31][CH2:32][C:33]([OH:35])=[O:34])[C:9]([C:11]1[CH:30]=[CH:29][C:14]2[N:15]([CH3:28])[C:16]([CH2:18][NH:19][C:20]3[S:21][C:22]([C:25](=[NH:26])[NH2:27])=[CH:23][N:24]=3)=[N:17][C:13]=2[CH:12]=1)=[O:10]

Participants

Reactant 2

HCID 14798Sodium Hydroxide

HCID 135690254HCID 135690254, compound

Product 1

HCID 135690256HCID 135690256, compound

Procedure

Prepared analogously to Example 26 from 1-methyl-2-[N-(5-amidinothiazol-2-yl)aminomethyl]benzimidazol-5-yl-carboxylic acid-N-(2-pyridyl)-N-(2-ethoxycarbonylethyl)amide hydrochloride and sodium hydroxide solution.

Sources & evidence

ORD record: ord-2588b621aea54d498dff4da11981c79b
Source dataset: uspto-grants-2004_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06710055B2

Reaction notes

Loading…