Nitric Acid → HCID 86628855, compound

HRID 504082Notes

Reaction equation

HRID 504082 reaction equation
[N+:1]([O-:4])([OH:3])=[O:2].[NH2:5][C@H:6]([C:11]([OH:13])=[O:12])[CH2:7][CH2:8][CH2:9][NH2:10].[N+:14]([O-:17])([OH:16])=[O:15].[NH2:18][C@H:19]([C:24]([OH:26])=[O:25])[CH2:20][CH2:21][CH2:22][NH2:23]>O>[N+:1]([O-:4])([OH:3])=[O:2].[N+:14]([O-:17])([OH:16])=[O:15].[NH2:5][C@H:6]([C:11]([OH:13])=[O:12])[CH2:7][CH2:8][CH2:9][NH2:10].[N+:1]([O-:4])([OH:3])=[O:2].[N+:1]([O-:4])([OH:3])=[O:2].[N+:1]([O-:4])([OH:3])=[O:2].[NH2:18][C@H:19]([C:24]([OH:26])=[O:25])[CH2:20][CH2:21][CH2:22][NH2:23]

Participants

6

Reactant 3

HCID 944Nitric AcidHCID 6262L-(-)-OrnithineHCID 86628857HCID 86628857, compound

Product 2

HCID 86628855HCID 86628855, compoundHCID 86628856HCID 86628856, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

Applicants have cost-effectively synthesized Ornithine Nitrate by combining nitric acid and Ornithine, mixing with water, and leaving to crystallize. Further nitratization can take place, yielding Ornithine Dinitrate or Ornithine Trinitrate. An alternative implementation comprises using Nitrous Acid (HNO2) instead of Nitric Acid (HNO3), thus yielding Ornithine Nitrite. Ornithine Nitrite has the same effects as Ornithine Nitrate, the only difference being that it requires one less step to yield Nitric Oxide (NO—). Mixed salts may also be used, such as in the non-limiting example of Ornithine Nitrate-Orotate.

Workup

  1. customleaving
  2. customto crystallize

Sources & evidence

ORD record
ord-00379cca06424d9eb355aefd62c65c9d
Source dataset
uspto-grants-2010_08
Patent number
US07777074B2

Reaction notes

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