反应详情

{(S)-1-Benzyl-2-[(E)-2-methylamino-phenylimino]-ethyl}-carbamic acid benzyl ester (0.075 g, 0.20 mmol) was dissolved in absolute ethanol (7 mL) and treated with 10% palladium on carbon (0.040 g). The resulting suspension was shaken under 60-65 psi H2 at room temperature for 16 h. The suspension was filtered and the filter cake washed with MeOH (−100 mL), and the combined filtrates concentrated in vacuo to give N-[(S)-2-Amino-3-phenyl-prop-(E)-ylidene]-N′-methyl-benzene-1,2-diamine, as a light yellow oil (0.052 g, approximately quantitative yield): ES+ LC/MS m/e 238 (M+H), RT=3.12 min.

1. filtrationThe suspension was filtered
2. washthe filter cake washed with MeOH (−100 mL)
3. concentrationthe combined filtrates concentrated in vacuo