HRID50425

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID81514

Butanoyl chloride, 3,3-dimethyl-

C6H11ClO

结构：CCc1nc2c(C)cc(C)nc2n1-c1ccc(CCNC(=O)NS(=O)(=O)c2ccc(C)cc2)cc1

HCID9935367

未命名化合物

PRODUCTS

生成物

结构：Cc1ccc(S(=O)(=O)NC(=O)NCCc2ccc(-n3c(CC(C)(C)C)nc4c(C)cc(C)nc43)cc2)cc1

HCID21875624

未命名化合物

PROCEDURE

实验过程

The title compound was prepared according to the procedure described in step 5 of Example 1 from 2-{4-[(3-amino-4,6-dimethyl-2-pyridinyl)amino]phenyl]ethanol (step 4 of Example 1) and tert-butylacetyl chloride.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-061b30b5d253412e930b1e05f200a656
来源数据集: uspto-grants-2004_03
DOI: 10.6084/m9.figshare.5104873.v1
专利: US06710054B2
来源说明: uspto-grants-2004_03

反应 SMILES

C(C1[N:13]([C:14]2[CH:19]=[CH:18][C:17]([CH2:20][CH2:21][NH:22][C:23]([NH:25][S:26]([C:29]3[CH:34]=[CH:33][C:32]([CH3:35])=[CH:31][CH:30]=3)(=[O:28])=[O:27])=[O:24])=[CH:16][CH:15]=2)[C:6]2=[N:7][C:8]([CH3:12])=[CH:9][C:10]([CH3:11])=[C:5]2[N:4]=1)C.[C:36]([CH2:40][C:41](Cl)=O)([CH3:39])([CH3:38])[CH3:37]>>[CH3:12][C:8]1[N:7]=[C:6]2[N:13]([C:14]3[CH:15]=[CH:16][C:17]([CH2:20][CH2:21][NH:22][C:23]([NH:25][S:26]([C:29]4[CH:30]=[CH:31][C:32]([CH3:35])=[CH:33][CH:34]=4)(=[O:27])=[O:28])=[O:24])=[CH:18][CH:19]=3)[C:41]([CH2:40][C:36]([CH3:37])([CH3:38])[CH3:39])=[N:4][C:5]2=[C:10]([CH3:11])[CH:9]=1