Naphthalenesulfonamide → 2-ethyl-5,7-dimethyl-3-{4-[2-({[(1-naphthylsulfonyl)amino]carbonyl}amino)ethyl]phenyl}-3H-imidazo[4,5-b]pyridine

Participants

Role	Name	HCID	Charge
Reactant	Naphthalenesulfonamide	HCID 163571	—
Reactant	3-{4-[2-({[(4-biphenylsulfonyl)amino]carbonyl}amino)ethyl]phenyl}-2-ethyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridine	HCID 21875619	—
Product	2-ethyl-5,7-dimethyl-3-{4-[2-({[(1-naphthylsulfonyl)amino]carbonyl}amino)ethyl]phenyl}-3H-imidazo[4,5-b]pyridine	HCID 21875982	—

Reaction Steps

The title compound was prepared according to the procedure described in step 2 of Example 18 from phenyl 2-[4-(2-ethyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridin-3-yl)phenyl]ethylcarbamate (step 1 of Example 18) and 1-naphtylsulfonamide (Arnswald, M.; Neumann, W. P. Chem. Ber., 1991, 124, 1997; Khorgami, M. H. Synthesis, 1972, 574).

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US06710054B2
Source dataset	uspto-grants-2004_03
ORD ID	ord-a7d2b85622224ebf95f709ab570bc5cc
Source note	uspto-grants-2004_03