Hydrochloric Acid → 2-[4-(2-Ethyl-5,7-dimethyl-3H-imidazo[4,5-B]pyridin-3-YL)phenyl]-1-methylethyl (4-methylphenyl)sulfonylcarbamate mono-hydrochloride

Participants

Reaction Steps

To a solution of 2-[4-(2-ethyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridin-3-yl)phenyl]-1-methylethyl (4-methylphenyl)sulfonylcarbamate (Example 7, 694 mg, 1.37 mmol) in methanol (4 ml) was added 10% HCl in methanol (2 ml) at room temperature. This mixture was concentrated, and treated with diethylether to afford 624 mg (90%) of the title compound as a slight yellow solid.

Provenance & Evidence