反应详情

In a manner similar to the method described in Example 1e, E/Z-6-chloro-3-[5-chloro-2-(2-methoxycarbonyl-2-methyl-propoxy)-benzylidene]-2-oxo-2,3-dihydro-indole-1-carboxylic acid tert-butyl ester (4.5 g, 9 mmol) was reacted with 1-(5-Fluoro-2-methylphenyl)-3-trimethylsilyoxy-2-aza-1,3-butadiene (63 mmol) in toluene to give title compound as a white solid (Yield: 300 mg, 5.5%).