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HRID 50448作成日：2026年10月26日

2,4-Dichloro-5-nitrobenzotrifluoride → (1r)-2-{4-[6-Chloro-2-ethyl-5-(trifluoromethyl)-1h-benzimidazol-1-yl]phenyl}-1-methylethyl (4-methylphenyl)sulfonylcarbamate

https://huagongshe.com/reaction/50448

反応式

関与物質

役割名称HCID仕込み量
反応物2,4-Dichloro-5-nitrobenzotrifluorideHCID 621179—
反応物(1R)-2-[4-(5-Acetyl-2-ethyl-1H-benzimidazol-1-YL)phenyl]-1-methylethyl (4-methylphenyl)sulfonylcarbamateHCID 86759399—
生成物(1r)-2-{4-[6-Chloro-2-ethyl-5-(trifluoromethyl)-1h-benzimidazol-1-yl]phenyl}-1-methylethyl (4-methylphenyl)sulfonylcarbamateHCID 91091514—

反応手順

The title compound was prepared according to the procedure described in step 1 of Example 162 from 2,4-dichloro-5-nitrobenzotrifluoride and (2R)-1-(4-aminophenyl)-2-propanol (step 2 of Example 249).

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US06710054B2
出典データセットuspto-grants-2004_03
ORD IDord-b8fda62f08b94d5992ff3866f93cf372
出典メモuspto-grants-2004_03