HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyrrolidine → HCID 86632061, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyrrolidine | HCID 31268 | — |
| Reactant | 6-Chloro-1,3-dihydroindol-2-one | HCID 736344 | — |
| Reactant | HCID 819983 | HCID 819983 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 86632061 | HCID 86632061 | 74.6% |
Reaction Steps
In a manner similar to the method described in Example 227b, (4-chloro-2-formyl-phenoxy)-acetic acid methyl ester (34 g, 149 mmol) was reacted with 6-chlorooxindole (20.7 g, 124 mmol) and pyrrolidine (10.58 g, 149 mmol) in methanol to give title compound as a yellow solid (35 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07776875B2 |
| Source dataset | uspto-grants-2010_08 |
| ORD ID | ord-d6bec6d09415418c940baa52894ce357 |
| Source note | uspto-grants-2010_08 |