HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyrrolidine → HCID 86617599, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyrrolidine | HCID 31268 | — |
| Reactant | 6-Chloro-1,3-dihydroindol-2-one | HCID 736344 | — |
| Reactant | HCID 57565968 | HCID 57565968 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 86617599 | HCID 86617599 | 131.9% |
Reaction Steps
In a manner similar to the method described in Example 1b, [2-(4-Chloro-2-formyl-phenoxy)-ethyl]-carbamic acid tert-butyl ester (8 g, 27 mmol) was reacted with 6-chloro-1,3-dihydro-indol-2-one (4.5 g, 27 mmol) and pyrrolidine (2.1 g, 30 mmol) in methanol (70 mL) to give title compound as a yellow solid (16 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07776875B2 |
| Source dataset | uspto-grants-2010_08 |
| ORD ID | ord-763d915afe20489e923185b548f46268 |
| Source note | uspto-grants-2010_08 |