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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 50453Generated: October 27, 2026

1,2-dimethyl-1H-imidazole-4-sulfonamide → 2-{4-[6-chloro-2-ethyl-5-(trifluoromethyl)-1H-benzimidazol-1-yl]phenyl}ethyl-(1,2-dimethyl-1H-imidazol-4-yl)sulfonylcarbamate

https://huagongshe.com/reaction/50453

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,2-dimethyl-1H-imidazole-4-sulfonamideHCID 2758563—
Reactant2-{4-[6-chloro-2-ethyl-5-(trifluoromethyl)-1H-benzimidazol-1-yl]phenyl}ethyl phenyl carbonateHCID 21876409—
Product2-{4-[6-chloro-2-ethyl-5-(trifluoromethyl)-1H-benzimidazol-1-yl]phenyl}ethyl-(1,2-dimethyl-1H-imidazol-4-yl)sulfonylcarbamateHCID 21876048—

Reaction Steps

The title compound was prepared according to the procedure described in step 2 of Example 243 from 2-{4-[6-chloro-2-ethyl-5-(trifluoromethyl)-1H-benzimidazol-1-yl]phenyl}ethyl phenyl carbonate and 1,2-dimethyl-1H-imidazol-4-ylsulfonamide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06710054B2
Source datasetuspto-grants-2004_03
ORD IDord-39c5133b8ccb40c4a679990081202151
Source noteuspto-grants-2004_03