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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 50456Generated: November 1, 2026

Acetic Anhydride → HCID 21876062, compound

https://huagongshe.com/reaction/50456

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetic AnhydrideHCID 7918—
Reactant2-amino-5,7-dimethyl-3-(4-{2-[({[(4-methylphenyl)sulfonyl]amino}carbonyl)amino]ethyl}phenyl)-3H-imidazo[4,5-b]pyridineHCID 21875860—
SolventPyridineHCID 1049—
ProductHCID 21876062HCID 218760625%

Reaction Steps

2-amino-5,7-dimethyl-3-(4-{2-[({[(4-methylphenyl)sulfonyl]amino}carbonyl)amino]ethyl}phenyl)-3H-imidazo[4,5-b]pyridine (73 mg) was treated with pyridine (1 ml) and Ac2O (0.2 ml) at room temperature for 3 hours. After evaporation in vacuo, the residue was purified by preparative TLC (hexane/acetone=1/1) to afford 4 mg (5%) of the title compounds.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06710054B2
Source datasetuspto-grants-2004_03
ORD IDord-500ce42b750f460792492feb90a93235
Source noteuspto-grants-2004_03