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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 504598Generated: November 2, 2026

1-(5-Fluoro-2-methylphenyl)-3-trimethylsilyoxy-2-aza-1,3-butadiene → HCID 74928717, compound

https://huagongshe.com/reaction/504598

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(5-Fluoro-2-methylphenyl)-3-trimethylsilyoxy-2-aza-1,3-butadieneHCID 70178504—
ReactantHCID 131728301HCID 131728301—
SolventTolueneHCID 1140—
ProductHCID 74928717HCID 749287179.7%

Reaction Steps

In a manner similar to the method described in Example 10d, E/Z-6-chloro-3-(5-chloro-2-methanesulfinylmethoxy-benzylidene)-2-oxo-2,3-dihydro-indole-1-carboxylic acid tert-butyl ester (400 mg, 0.83 mmol) was reacted with 1-(5-fluoro-2-methyl-phenyl)-3-trimethylsilyoxy-2-aza-1,3-butadiene (5 mmol) in toluene to give the title compound as a white solid (45 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07776875B2
Source datasetuspto-grants-2010_08
ORD IDord-77656b1688444564a4d079303530d9a5
Source noteuspto-grants-2010_08