1-(5-Fluoro-2-methylphenyl)-3-trimethylsilyoxy-2-aza-1,3-butadiene → HCID 86632111, compound

Participants

Reaction Steps

In a manner similar to the method described in Example 10d, E/Z-1-(1-tert-butoxy-vinyl)-6-chloro-3-[5-chloro-2-(tetrahydro-pyran-4-ylmethoxy)-benzylidene]-1,3-dihydro-indol-2-one (2 g, 3.97 mmol) was reacted with 1-(5-fluoro-2-methyl-phenyl)-3-trimethylsilyoxy-2-aza-1,3-butadiene (20 mmol) in toluene to give the title compound as a white solid (770 mg).

Provenance & Evidence