Lawesson's reagent → 7-[methyl(2-thienylsulfonyl)amino]-1H-indole-2-carbothioamide

Beteiligte Stoffe

Reaktionsbedingungen

Reaktionsschritte

A mixture of 7-[methyl(2-thienylsulfonyl)amino]-1H-indole-2-carboxamide (11.47 g), Lawesson's reagent (15.2 g) and tetrahydrofuran (150 ml) was stirred at 50° C. for 4 hr. The reaction mixture was concentrated, and the resulting crystals were filtrated, washed with toluene, and dried to give the title compound (11.16 g, yield 93%) as yellow crystals. melting point 239-240° C.

Herkunft & Nachweise