methyl 2-methyl-2-(4-nitro-1H-imidazol-1-yl)propanoate → HCID 68460522, 화합물

HRID 505038노트

반응식

HRID 505038 반응식
[CH3:1][O:2][C:3](=[O:15])[C:4]([CH3:14])([N:6]1[CH:10]=[C:9]([N+:11]([O-])=O)[N:8]=[CH:7]1)[CH3:5].[F:16][C:17]1[CH:18]=[C:19]2[C:24](=[C:25]([F:27])[CH:26]=1)[CH2:23][CH:22]([NH:28][CH:29]([CH3:33])[C:30](O)=[O:31])[CH2:21][CH2:20]2>>[CH3:1][O:2][C:3](=[O:15])[C:4]([N:6]1[CH:10]=[C:9]([NH:11][C:30](=[O:31])[CH:29]([NH:28][CH:22]2[CH2:21][CH2:20][C:19]3[C:24](=[C:25]([F:27])[CH:26]=[C:17]([F:16])[CH:18]=3)[CH2:23]2)[CH3:33])[N:8]=[CH:7]1)([CH3:14])[CH3:5]

참가 물질

3

반응물 2

HCID 67164903methyl 2-methyl-2-(4-nitro-1H-imidazol-1-yl)propanoateHCID 68461760HCID 68461760, 화합물

생성물 1

HCID 68460522HCID 68460522, 화합물

실험 절차

2-Methyl-2-(4-nitro-imidazol-1-yl)-propionic acid methyl ester was reduced and coupled with 2-(6,8-Difluoro-1,2,3,4-tetrahydro-naphthalen-2-ylamino)-propionic acid to afford the title compound; MS 421.5 m/z (M+1).

출처 및 근거

ORD 기록
ord-bfd21a03899444c2ab54f74e944b3379
출처 데이터셋
uspto-grants-2010_08
특허 번호
US07781435B2

반응 노트

불러오는 중…