HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(((Tert-butoxy)carbonyl)amino)pentanoic acid → {1-[1-(3-oxo-butyl)-1H-imidazol-4-ylcarbamoyl]-butyl}-carbamic acid tert-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(((Tert-butoxy)carbonyl)amino)pentanoic acid | HCID 302433 | — |
| Reactant | 4-(4-nitro-1H-imidazol-1-yl)butan-2-one | HCID 15192332 | — |
| Product | {1-[1-(3-oxo-butyl)-1H-imidazol-4-ylcarbamoyl]-butyl}-carbamic acid tert-butyl ester | HCID 68463268 | — |
Reaction Steps
4-(4-nitro-1H-imidazol-1-yl)butan-2-one was reduced and coupled with 2-[(tert-butoxycarbonyl)amino]pentanoic acid to afford the title compound; MS 353 m/z (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07781435B2 |
| Source dataset | uspto-grants-2010_08 |
| ORD ID | ord-93300f67e484497aaf5dfd7698dcb9fa |
| Source note | uspto-grants-2010_08 |