HRID505054

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID4076431

6,8-Difluoro-2-tetralone

C10H8F2O

结构：CCCC(N)C(=O)Nc1cn(C(C)(C)CCNC(C)c2ccccc2)cn1

HCID86611459

未命名化合物

PRODUCTS

生成物

结构：CCC[C@H](NC1CCc2cc(F)cc(F)c2C1)C(=O)Nc1cn(C(C)(C)CCN[C@H](C)c2ccccc2)cn1

HCID16113685

未命名化合物

PROCEDURE

实验过程

2-Amino-pentanoic acid {1-[1,1-dimethyl-3-(1-phenyl-ethylamino)-propyl]-1H-imidazol-4-yl}-amide was reacted with 6,8-Difluoro-3,4-dihydro-1H-naphthalen-2-one to afford the title: 538.6 m/z (M+1).

WORKUP

后处理

customto afford the title

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-b1e77d8b26274ea7a7706df6dd726de8
来源数据集: uspto-grants-2010_08
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07781435B2
来源说明: uspto-grants-2010_08

反应 SMILES

[CH3:1][C:2]([N:15]1[CH:19]=[C:18]([NH:20][C:21](=[O:27])[CH:22]([NH2:26])[CH2:23][CH2:24][CH3:25])[N:17]=[CH:16]1)([CH3:14])[CH2:3][CH2:4][NH:5][CH:6]([C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)[CH3:7].[F:28][C:29]1[CH:30]=[C:31]2[C:36](=[C:37]([F:39])[CH:38]=1)[CH2:35][C:34](=O)[CH2:33][CH2:32]2>>[CH3:14][C:2]([N:15]1[CH:19]=[C:18]([NH:20][C:21](=[O:27])[C@@H:22]([NH:26][CH:34]2[CH2:33][CH2:32][C:31]3[C:36](=[C:37]([F:39])[CH:38]=[C:29]([F:28])[CH:30]=3)[CH2:35]2)[CH2:23][CH2:24][CH3:25])[N:17]=[CH:16]1)([CH3:1])[CH2:3][CH2:4][NH:5][C@@H:6]([C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)[CH3:7]