Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Bromoacetic Acid → {6-Chloro-3-[4-(2,6-dimethoxy-phenyl)-piperidine-1-carbonyl]-indol-1-yl}-acetic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Bromoacetic Acid | HCID 6227 | — |
| 반응물 | (6-chloro-1H-indol-3-yl)-[4-(2,6-dimethoxy-phenyl)-piperidin-1-yl]-methanone | HCID 16062188 | — |
| 생성물 | {6-Chloro-3-[4-(2,6-dimethoxy-phenyl)-piperidine-1-carbonyl]-indol-1-yl}-acetic acid | HCID 66744387 | — |
반응 단계
Following general procedure II, the alkylation of (6-chloro-1H-indol-3-yl)-[4-(2,6-dimethoxy-phenyl)-piperidin-1-yl]-methanone (preparation described herein), with (commercially available) bromo-acetic acid gave the title compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07781436B2 |
| 출처 데이터셋 | uspto-grants-2010_08 |
| ORD ID | ord-0535e157a9e54865a1b38164d02ecee7 |
| 출처 메모 | uspto-grants-2010_08 |