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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 505138Generated: October 30, 2026

Hydrochloric Acid → HCID 66744531, compound

https://huagongshe.com/reaction/505138

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantN-BOC-ethylenediamineHCID 187201—
ReactantHCID 66743711HCID 66743711—
ProductHCID 66744531HCID 66744531—

Reaction Steps

Analogous to general procedure I, the coupling of {6-chloro-3-[4-(2-trifluoromethyl-phenyl)-piperidine-1-carbonyl]-indol-1-yl}-acetic acid (prepared herein) with (commercially available) (2-amino-ethyl)-carbamic acid tert-butyl ester gave, after treatment with HCl, the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07781436B2
Source datasetuspto-grants-2010_08
ORD IDord-24e64a0d0860455fb94147023d10490c
Source noteuspto-grants-2010_08