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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 505141Generated: October 30, 2026

2-Chloroethylamine → [1-(2-Amino-ethyl)-6-chloro-1H-indol-3-yl]-[4-(2,3-dihydro-benzofuran-7-yl)-piperidin-1-yl]-methanone

https://huagongshe.com/reaction/505141

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-ChloroethylamineHCID 13369—
ReactantHCID 59429622HCID 59429622—
Product[1-(2-Amino-ethyl)-6-chloro-1H-indol-3-yl]-[4-(2,3-dihydro-benzofuran-7-yl)-piperidin-1-yl]-methanoneHCID 59429611—

Reaction Steps

Following general procedure II, the alkylation of (6-chloro-1H-indol-3-yl)-[4-(2,3-dihydro-benzofuran-7-yl)-piperidin-1-yl]-methanone (preparation described herein), with (commercially available) 2-chloro-ethylamine gave the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07781436B2
Source datasetuspto-grants-2010_08
ORD IDord-566cd70e1f9d44949e67b3de9d954f9b
Source noteuspto-grants-2010_08